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Dr. Zeban Kolen

Associate Director, Biological Assays at Synthon

Dr. Zeban Kolen is Associate Director biopotency assays at Synthon Biopharmaceuticals BV. Dr. Kolen conducted his PhD at the Laboratory of Hematology of the Radboud University Medical Center, Nijmegen, The Netherlands, where he studied chimerism in haematopoietic reconstitution after allogeneic stem cell transplantation and donor leukocyte infusions. He then joined Synthon BV, and was involved in the start-up and successful fruition of Synthon’s Biopharmaceutical ambitions, with a growing portfolio in oncology and autoimmune diseases.

During his career he has gained expertise with development and validation of robust and fit for purpose potency assays, applying analytical quality by design (aQbD) concepts. The latter is strengthened by his interest in process improvement and acquisition of a Six Sigma Black Belt. Statistical thinking and concepts have been a main focus in leading his group at Synthon Biopharmaceuticals, and a main principle taught during his trainings/seminars.



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